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Emotional wellbeing, Healthy mood, Neurotransmitter support, Joint health
Adults seeking mood and emotional balance support or those looking for daily joint comfort support.
Take 1 tablet with water, 1 to 4 times daily; consider starting with 1 tablet per day and increase as needed; taking on an empty stomach may enhance absorption, and morning or early-day use may be preferable if it feels energising.
SAMe donates methyl groups in methylation reactions that influence neurotransmitter synthesis and also contributes sulphur groups for cartilage components, which may support mood balance and joint comfort.
Caution: May interact with antidepressant medicines and may not be appropriate for people with bipolar disorder because it can affect neurotransmitter activity; start with lower intake if sensitive to stimulatory effects and take earlier in the day if it affects sleep.
Label Warning: Adults only. Consult a healthcare provider before use if pregnant or breastfeeding, taking antidepressant medication, or if you have bipolar disorder.
Who should be cautious: People taking antidepressants or with mood disorders may be more sensitive to SAMe’s effects on neurotransmitters. Those with a history of manic episodes or bipolar disorder should seek medical advice before use. If you are pregnant or breastfeeding, discuss with a healthcare provider first.
Storage: Store in a cool, dry place.
This product is guaranteed authentic and backed by our easy returns and refunds policy. Details
Glucosamine and chondroitin may support joint health and flexibility, complementing SAM-e's potential benefits for joint comfort and mobility.
AI generated. Not medical advice.
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Precursor to glutathione, a cellular antioxidant believed to be a "Master Nutrient" for longevity.
As a dietary supplement, take one tablet one to four times per day with water.
Microcrystalline cellulose (plant fibre), croscarmellose sodium, ascorbyl palmitate, silica, ascorbic acid, citric acid, enteric coating [methacrylic acid copolymer, hydroxypropyl methylcellulose, hydroxypropyl cellulose, calcium carbonate, riboflavin (colourant), propylene glycol].
For adults only. Consult your healthcare provider before use if you are pregnant or breastfeeding, taking antidepressant medication or if you have bipolar disorder.
Keep out of reach of children. Do not use if seal is broken. Store in a cool, dry place.
While iHerb strives to ensure the accuracy of its product images and information, some manufacturing changes to packaging and/or ingredients may be pending update on our site. Although items may occasionally be despatched with alternative packaging, freshness is always guaranteed. We recommend that you read labels, warnings and directions of all products before use and do not rely solely on the information provided by iHerb. This website has been machine translated as a courtesy to customers. iHerb does not represent or warrant that the translations are complete or error-free and iHerb is not responsible for any translation errors or omissions.
| Supplement information | ||
| Serving Size:one tablet | ||
| Amount per serving | %Reference Intake | |
| SAM-e (S-Adenosyl L-Methionine) (from 800 mg of S-adenosyl-L-methionine tosylate disulphate) | 400 mg | * |
| *Reference intake not established. | ||
